Browse wiki

From MurrayWiki
Jump to: navigation, search
Biomolecular resource utilization in elementary cell-free gene circuits
Abstract We present a detailed dynamical model of t
We present a detailed dynamical model of the behavior of transcription-translation circuits in vitro that makes explicit the roles played by essential molecular resources. A set of simple two-gene test circuits operating in a cell-free biochemical ‘breadboard’ validate this model and highlight the consequences of limited resource availability. In particular, we are able to confirm the existence of biomolecular ‘crosstalk’ and isolate its individual sources. The implications of crosstalk for biomolecular circuit design and function are discussed.
circuit design and function are discussed.  +
Authors Dan Siegal-Gaskins, Vincent Noireaux, and Richard M. Murray  +
Funding Biomolecular Breadboards for Prototyping and Debugging Synthetic Biocircuits +
ID 2012p  +
Source 2013 American Control Conference (ACC)  +
Tag snm13-acc  +
Title Biomolecular resource utilization in elementary cell-free gene circuits +
Type Conference Paper  +
Categories Papers
Modification date
This property is a special property in this wiki.
17 May 2016 15:17:58  +
URL
This property is a special property in this wiki.
http://www.cds.caltech.edu/~murray/preprints/snm13-acc.pdf  +
hide properties that link here 
Biomolecular resource utilization in elementary cell-free gene circuits + Title
 

 

Enter the name of the page to start browsing from.