Browse wiki
From MurrayWiki
| Biomolecular resource utilization in elementary cell-free gene circuits |
| Abstract |
We present a detailed dynamical model of t … We present a detailed dynamical model of the behavior of
transcription-translation circuits in vitro that makes explicit the roles
played by essential molecular resources. A set of simple two-gene test
circuits operating in a cell-free biochemical âbreadboardâ validate this
model and highlight the consequences of limited resource availability. In
particular, we are able to confirm the existence of biomolecular âcrosstalkâ
and isolate its individual sources. The implications of crosstalk for
biomolecular circuit design and function are discussed. circuit design and function are discussed. +
|
|---|---|
| Authors | Dan Siegal-Gaskins, Vincent Noireaux, and Richard M. Murray + |
| Funding | Biomolecular Breadboards for Prototyping and Debugging Synthetic Biocircuits + |
| ID | 2012p + |
| Source | 2013 American Control Conference (ACC) + |
| Tag | snm13-acc + |
| Title | Biomolecular resource utilization in elementary cell-free gene circuits + |
| Type | Conference Paper + |
| Categories | Papers |
| Modification date This property is a special property in this wiki.
|
17 May 2016 15:17:58 + |
| URL This property is a special property in this wiki.
|
http://www.cds.caltech.edu/~murray/preprints/snm13-acc.pdf + |
| hide properties that link here |
| Biomolecular resource utilization in elementary cell-free gene circuits + | Title |
|---|
