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Analysis and design of a synthetic transcriptional network for exact adaptation
Abstract This paper presents a mathematical model f …
This paper presents a mathematical model for a synthetic transcriptional regulatory network in vitro. This circuit design resembles one of the well-known network motifs, the inco- herent feed-forward loop, in which an activator regulates both a gene and a repressor of the gene. Through mathematical analysis, we show how the circuit can be controlled to demonstrate exact adaptation to input signals.
nstrate exact adaptation to input signals.  +
Authors Jongmin Kim and Richard M. Murray  +
Funding Molecular Programming Project +
ID 2011e  +
Source 2011 IEEE Biomedical Circuits and Systems (BioCAS) Conference (submitted)  +
Tag km11-biocas  +
Title Analysis and design of a synthetic transcriptional network for exact adaptation +
Type Conference Paper  +
Categories Papers
Modification date
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29 October 2017 14:30:30  +
URL
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http://www.cds.caltech.edu/~murray/preprints/km11-biocas_s.pdf  +
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