Jake Beal, 1 Oct 2019

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Jake Beal will visit Caltech on 1 Oct 2019. If you would like to meet with him, please sign up below.

Schedule

  • 9:00a: RMM group meeting, 111 Keck (if interested)
  • 11:00a: James
  • 11:45a: seminar setup
  • 12:00p: Seminar, 111 Keck (abstract below)
  • 1:00p: Lunch with Andrey Shur, Sam Clamons
  • 1:45p: Lab tour and calibration discussion (Andrey, Sam, Mark, Miki)
  • 2:30p: John Marken
  • 3:15p: Elin Larsson
  • 4:00p: Ayush and Chelsea
  • 4:45p: Wrap up with Richard

Talk abstract

Paths to Resilient Biological Information Processing
Jake Beal (Raytheon BBN)

1 October (Tue), 12-1 pm, 111 Keck

Engineered information processing in biological organisms has potential revolutionary implications across many application domains. A major barrier, however, has been the fragility of biological information processing devices to changes in their usage, genetic context, or operating environment. Engineering resilient information processing, however, is not just a biological challenge, but a three-way interplay between device performance, measurement quality, and model accuracy. In this talk, I will discuss how the interplay between these three aspects offer multiple paths for improving the resilience of biological information processing, giving examples of recent progress in reproducible and comparable measurement, the development of high-performance devices and insulators, and precision prediction of genetic circuits.

Dr. Jacob Beal is a Senior Scientist at Raytheon BBN Technologies, where he leads research on synthetic biology and distributed systems engineering. His work in synthetic biology includes development of methods for calibrated flow cytometry, precision analysis and design of genetic regulatory networks, engineering of biological information processing devices, standards for representation and communication of biological designs, and signature-based detection of pathogenic sequences.