Difference between revisions of "Supplement: Biomolecular Feedback Systems"
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** Cellular Subsystems | ** Cellular Subsystems | ||
* Chapter 3: {{BFS pdf|Dynamic Behavior|bfs-dynamics|11Jul12}} | * Chapter 3: {{BFS pdf|Dynamic Behavior|bfs-dynamics|11Jul12}} | ||
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** Analysis Near Equilibria | ** Analysis Near Equilibria | ||
** Robustness | ** Robustness | ||
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** Oscillatory Behavior | ** Oscillatory Behavior | ||
** Bifurcations | ** Bifurcations | ||
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** Activator-repressor Clock | ** Activator-repressor Clock | ||
** An Incoherent Feedforward Loop (IFFL) | ** An Incoherent Feedforward Loop (IFFL) | ||
+ | ** Bacterial Chemotaxis | ||
* Chapter 6: {{BFS pdf|Interconnecting Components|bfs-modules|11Jul12}} | * Chapter 6: {{BFS pdf|Interconnecting Components|bfs-modules|11Jul12}} | ||
** Input/Output Modeling and the Modularity Assumption | ** Input/Output Modeling and the Modularity Assumption | ||
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** Retroactivity in Signaling Systems | ** Retroactivity in Signaling Systems | ||
** Insulation Devices: Retroactivity Attentuation | ** Insulation Devices: Retroactivity Attentuation | ||
+ | ** A Case Study on the Use of Insulation Devices | ||
* Chapter 7: {{BFS pdf|Design Tradeoffs|bfs-tradeoffs|11Jul12}} | * Chapter 7: {{BFS pdf|Design Tradeoffs|bfs-tradeoffs|11Jul12}} | ||
− | ** | + | ** Competition for Shared Cellular Resources |
− | ** Stochastic Effects: Design Tradeoffs | + | ** Stochastic Effects: Design Tradeoffs in Systems with Large Gains |
− | * Appendix A: | + | * Appendix A: A Primer on Control Theory |
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* Appendix A: Cell Biology Primer (from NCBI) | * Appendix A: Cell Biology Primer (from NCBI) |
Revision as of 17:32, 5 December 2013
Domitilla Del Vecchio (MIT) and Richard M. Murray (Caltech)
This textbook is intended for researchers interested in the application of feedback and control to biomolecular systems. The material has been designed so that it can be used in parallel with Feedback Systems as part of a course on biomolecular feedback and control systems, or as a standalone reference for readers who have had a basic course in feedback and
control theory. The supplement is being written by Domitilla Del Vecchio and Richard Murray based on a variety of presentations, lectures and notes.
Note: These notes are in draft form and may contain errors. Permission is granted to download and print a copy for individual use, but this material may not be reproduced, in whole or in part, without written consent from the author.
News (archive)
- 20 Jul 2013: Updated outline and new PDFs are being posted over the next month.
- 12 Jul 2012: Updated outline; new PDFs posted. A complete manuscript (PDF) is also available.
- 16 Jan 2012: Updated outline; new PDFs for all chapters and appendices (coming later today)
Contents
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Additional Information
- ASCC 2009 Workshop - Analysis and Design of Biomolecular Feedback Systems
- Engineering Principles in Biological Systems: 10-12 December 2008, Cold Spring Harbor Laboratory
- Design Principles in Biological Systems: 24-28 April 2008, Institute for Mathematics and Its Applications (IMA)
- Engineering Principles in Biological Systems: 6-8 December 2006, Cold Spring Harbor Laboratory