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Modeling Environmental Disturbances with the Chemical Master Equation |
Abstract |
In this paper we consider the problem of r … In this paper we consider the problem of repre- senting a biological system and its environment using a stochas- tic modeling framework. We first introduce a decomposition of the global chemical reaction system into two systems: a system of interest and its environment. We then present and derive a decomposition of the chemical master equation to achieve a representation describing the dynamics of the system of inter- est, perturbed by an environmental disturbance. We use this decomposition to model examples of two types of environmental disturbances: the disturbance a system experiences through loading effects from limited resources and the disturbance a system experiences when perturbed by an antibiotic that modifies transcription or translation rates. difies transcription or translation rates. +
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Authors | Enoch Yeung, James L. Beck, and Richard M. Murray + |
ID | 2013b + |
Source | Submitted, 2013 Conference on Decision and Control (CDC) + |
Tag | ybm13-cdc + |
Title | Modeling Environmental Disturbances with the Chemical Master Equation + |
Type | Conference Paper + |
Categories | Papers |
Modification date This property is a special property in this wiki.
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15 May 2016 06:15:24 + |
URL This property is a special property in this wiki.
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http://www.cds.caltech.edu/~murray/preprints/ybm13-cdc_s.pdf + |
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Modeling Environmental Disturbances with the Chemical Master Equation + | Title |
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