File:Message Routing Schematic.png

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Fig. 1: (a) A 3-node linear signal path built with two guide RNAs and one integrase. The signal plasmid originally starts in Cell A, and cannot be sent to Cell C as the address contains the C gRNA binding site. However, once the signal plasmid enters Cell B, the TP901 integrase swaps the C binding site for an A binding site. The signal plasmid is now unable to return to Cell A, but is now able to proceed to cell C. (b) A 4-node linear signal path built with three guide RNAs and two integrases.

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current18:58, 10 December 2018Thumbnail for version as of 18:58, 10 December 20181,986 × 956 (665 KB)Jmarken (Talk | contribs)Fig. 1: (a) A 3-node linear signal path built with two guide RNAs and one integrase. The signal plasmid originally starts in Cell A, and cannot be sent to Cell C as the address contains the C gRNA binding site. However, once the signal plasmid enters C...
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